You can easily Set the Pages Per Sheet option with this Online PDF Layout creator — WebDesignerSchool.com What are the major differences between a simple page and a multipage layout? The page is a fixed place, containing the content of your document, while a multipage document is made up of several pages and is thus much more flexible. Page-based layouts are also more suitable for content-rich text documents, though a multipage layout can also be used to display a large page with many graphic images (or to create a simple brochure). Multipage PDF layout (as implemented with Photoshop): The page-based PDF layout allows a number of different pages to be placed on the same page and has advantages such as using fewer file formats and being easier to maintain. This is best used for documents containing multiple or lengthy sections that require an extensive amount of background information or information pertaining to the section. Also, page-based layouts can be useful for creating e-books such as those published by O'Reilly Media. Pages also allow for easier content organization, as they can be placed using the following principles: Make page 1 the most important part of the page Use single pages for different types of content — for text, links, and other related content Use multiple pages, or pages on separate pages at one time Split pages, as it becomes confusing and distracting Create multiple page layouts, by setting different “page sets” for different types of data Make it look like one large page For a single page layout, create separate sheets, with each sheet having its own individual image, colors, font, size, alignment, etc. Multipage layout (as implemented with Illustrator): The page-based PDF layout allows a number of different pages to be placed on the same page and can be used to display pages that are only accessible while the rest of the page is obscured. The advantages in using the multipage format may include ease of use, more space, lower file sizes, lower file size consumption, better display, and better organization. Illustrator is not the most popular or widely used tool when it comes to creating multipage PDF forms, but it can be a good tool if you have a strong technical understanding of the format you are creating. Illustrator multipage PDF layout with multiple pages. Here are some examples of multipage PDF layout created by Illustrator. Multipage PDF layout created by Illustrator.